When six school friends meet up for a fourth of July celebration on a remote island off the Washington coast, what they expect is a harmless weekend filled with fun and partying. Unfortunately, when one of them brings along some cocaine to amp up the good times, what they get is a mind bending trip filled with horror, chaos and murder. Unbeknownst to the friends, a sadistic, right wing terrorist organization has secretly funneled a new bio-active drug into the market disguised as cocaine. Anyone who consumes the drug is then exposed to a virus that causes fits of psychotic rage. Only one girl, Brie, refuses to take the drug and she alone must fight to stay alive as everyone around her, including her fiancé, attempts to savagely kill her. Her only hope may be a detective who is desperately trying to unravel the mystery behind the sadistic terrorist plot and save Brie before it's too late. Trapped on the island, Brie must endure the unimaginable and survive a deadly game of cat and .